Rank Product Name Score
1 Pure Encapsulations - Systemic Enzyme Complex - Synergistic Formula to Support Muscle, Joint and Tissue Health - 180 Capsules Pure Encapsulations – Systemic Enzyme Complex – Synergistic Formula to Support Muscle, Joint and Tissue Health – 180 Capsules
Pure Encapsulations
9.9 GET ON AMAZON
2 Serrapeptase Enzymes by MaryRuth Serrapeptase Enzymes by MaryRuth’s – Vegan Serrapeptase High Potency Sinus Pills – Allergy Support – Plant Based, Vegan Capsule – Enteric Coated – 60 Count
MaryRuth Organics
9.8 GET ON AMAZON
3 Vitälzym Proteolytic Systemic Enzymes Liquid Gel Capsules with Serrapeptase, Anti-inflammatory Defense Treatment, Immune and Joint Support, Natural Ache Relief Plus Fertility Supplement (360 Capsules) Vitälzym Proteolytic Systemic Enzymes Liquid Gel Capsules with Serrapeptase, Anti-inflammatory Defense Treatment, Immune and Joint Support, Natural Ache Relief Plus Fertility Supplement (360 Capsules)
World Nutrition, Inc.
9.7 GET ON AMAZON
4 Garden of Life Joint Support Supplement - Wobenzym N Systemic Enzymes, 200 Tablets Garden of Life Joint Support Supplement – Wobenzym N Systemic Enzymes, 200 Tablets
Garden of Life
9.5 GET ON AMAZON
5 Pro-OneZyme Best Proteolytic Systemic Enzymes Supplement with Nattokinase & Seapose - 90 Capsules Pro-OneZyme Best Proteolytic Systemic Enzymes Supplement with Nattokinase & Seapose – 90 Capsules
WellnessOne
9.2 GET ON AMAZON
6 Excellacor – Proteolytic Systemic Enzymes Formula – with Enteric-Coated Serrapeptase - Total Body Support - 90 Vegetarian Capsules - AST Enzymes Excellacor – Proteolytic Systemic Enzymes Formula – with Enteric-Coated Serrapeptase – Total Body Support – 90 Vegetarian Capsules – AST Enzymes
AST Enzymes
8.9 GET ON AMAZON
7 Vitälzym Original Proteolytic Systemic Digestive Enzyme Formula Serrapeptase Source | Anti-Inflammatory Immune and Joint Support Increase Blood Flow Cardio Function | Healthy Men Women (90 Capsules) Vitälzym Original Proteolytic Systemic Digestive Enzyme Formula Serrapeptase Source | Anti-Inflammatory Immune and Joint Support Increase Blood Flow Cardio Function | Healthy Men Women (90 Capsules)
VITÄLZYM
8.5 GET ON AMAZON
8 Fibrenza Systemic Enzyme 500mg 60 Capsules Fibrenza Systemic Enzyme 500mg 60 Capsules
HCP Formulas
8.1 GET ON AMAZON
9 Medizym, Systemic Enzyme Formula, 200 Tablets Medizym, Systemic Enzyme Formula, 200 Tablets
Naturally Vitamins
8.0 GET ON AMAZON
10 Integrative Therapeutics - Bio-Zyme - Systemic Enzymes - Full-Strength Pancreatic Enzyme Complex to Support Digestive Health - 200 Tablets Integrative Therapeutics – Bio-Zyme – Systemic Enzymes – Full-Strength Pancreatic Enzyme Complex to Support Digestive Health – 200 Tablets
Integrative Therapeutics
7.8 GET ON AMAZON

Pure Encapsulations – Systemic Enzyme Complex – Synergistic Formula to Support Muscle, Joint and Tissue Health – 180 Capsules

Pure Encapsulations - Systemic Enzyme Complex - Synergistic Formula to Support Muscle, Joint and Tissue Health - 180 Capsules

    Features:

  • Muscular Health: Systemic Enzyme Complex is formulated to support the overall health of the musculoskeletal system.*
  • Muscle Comfort: Supports a healthy response to temporary muscle soreness and temporary joint discomfort associated with exercise.*
  • Joint & Cartilage Health: Promotes healthy connective tissue, as well as joint and cartilage health.*
  • Pure Quality: Our supplements are made with only premium ingredients sourced from trusted suppliers and guided by our nutritional experts, then carefully manufactured and tested to verify their potency and purity.
  • Pure Difference: What makes us different isn’t just our process or what goes into our supplements — what we leave out matters, too. All Pure Encapsulations products are FREE FROM many common allergens like wheat, eggs, tree nuts & peanuts, gluten, artificial colors, flavors & sweeteners, coatings and shellacs, GMOs, unnecessary binders, fillers & preservatives, and more.

Serrapeptase Enzymes by MaryRuth’s – Vegan Serrapeptase High Potency Sinus Pills – Allergy Support – Plant Based, Vegan Capsule – Enteric Coated – 60 Count

Serrapeptase Enzymes by MaryRuth

    Features:

  • Powerful Serrapeptase Capsules: We pair an advanced serrapeptase and protease enzyme complex with supporting vitamins and minerals to unlock the maximum benefits of serrapeptase on the body.
  • Advanced Enzyme Complex: We include more clean Serrapeptase (120,000 SPU) in every pill. Our added Protease Complex helps to efficiently digest all types of proteins. Pairing these enzymes with cofactor vitamins and minerals helps your body use the enzymes faster and more efficiently.
  • Easy Efficient Absorption: Our easy to take enzyme pills result in faster, more efficient health support. Safe & effective for men and women. Each bottle contains 60 pills, with a serving size of 1 capsule, and will last 1-2 months.

Vitälzym Proteolytic Systemic Enzymes Liquid Gel Capsules with Serrapeptase, Anti-inflammatory Defense Treatment, Immune and Joint Support, Natural Ache Relief Plus Fertility Supplement (360 Capsules)

Vitälzym Proteolytic Systemic Enzymes Liquid Gel Capsules with Serrapeptase, Anti-inflammatory Defense Treatment, Immune and Joint Support, Natural Ache Relief Plus Fertility Supplement (360 Capsules)

    Features:

  • Enteric Coated Advanced Delivery Method: Vitalzym high potency gel caps are unlike any tablet or powder based enzyme product available on the market today. Our formula contains no gluten, yeast or dairy and is designed to ensure maximum absorption into the bloodstream where it is then dispersed via your circulatory system throughout your body
  • Ingredients: Vitalzym Extra Strength premium softgels are the original, all-natural, vegetarian multi enzyme complex. Vitalzym was designed using a scientific research process to identify nature’s miracle ingredients that include Serrapeptase, Bromelain, Papain, Rutin, Amylase, Protease, Lipase and Amla Extract
  • Protect Your Health: Living well in modern times can be stressful and a source of pain at times. Vitalzym contains the most effective, purified vegan-based enzyme blend to promote healing, repair human bodily functions and leave you feeling clear and fresh
  • Small, Easy To Swallow Gel Caps: Our advanced encapsulations deliver reliable results that offer pure, potent enzymes with reliable consistency and unrivaled absorption rates. Due to the highly effective delivery rate most people need a smaller dosage, and less doses per day
  • Made In Japan: Created by a team of international scientists, Vitalzym works best when combined with exercise, proper fluid intake, and a healthy diet. It is important to be mindful of all aspects of your health. When used properly, Vitalzym can greatly increase your cardio, lung, blood flow, and immune response as well as provide joint, circulatory system and inflammation support and much more

Garden of Life Joint Support Supplement – Wobenzym N Systemic Enzymes, 200 Tablets

Garden of Life Joint Support Supplement - Wobenzym N Systemic Enzymes, 200 Tablets

    Features:

  • Supports the Body’s Natural Inflammation Response
  • Increases Flexibility and Mobility
  • Supports Joint and Tendon Health
  • Temporary Relief from Aches, Pains and Muscle Soreness due to Everyday Activity
  • Healthy Aging & normalized Inflammation

Pro-OneZyme Best Proteolytic Systemic Enzymes Supplement with Nattokinase & Seapose – 90 Capsules

Pro-OneZyme Best Proteolytic Systemic Enzymes Supplement with Nattokinase & Seapose - 90 Capsules

    Features:

  • UNIQUELY FORMULATED – ProOneZyme is the only supplement that contains 6 of the best quality proteolytic enzymes in one convenient vegan capsule. These ingredients include Bromelain, Nattokinase, Papain, Peptidase, Protease, Seaprose, Catalase and Rutin.
  • ALL NATURALLY MADE – Contains no wheat, yeast, soy or gluten. NO animal derivatives, sugars, artificial flavors, colors or fillers. It’s perfect for vegetarians and meat lovers alike!
  • PERFORMANCE DRIVEN – Proteolytic Systemic Enzymes gives active enzymes the body can use. They can also work in part to help digest food. When the body is happy; you feel younger and full of life.
  • POWERFUL AND PROVEN – Nattokinase and Seaprose is gentle on the stomach. ProOneZyme Capsules are designed to withstand stomach acid and release inside the intestinal tract where it is absorbed and used in the body.
  • 100% RISK FREE GUARANTEE! If for any reason you are not satisfied with ProOneZyme simply return any unused portion for a full no hassle, 30-Day Money-Back Guarantee! Third Party Tested and manufactured in a GMP Facility.

Excellacor – Proteolytic Systemic Enzymes Formula – with Enteric-Coated Serrapeptase – Total Body Support – 90 Vegetarian Capsules – AST Enzymes

Excellacor – Proteolytic Systemic Enzymes Formula – with Enteric-Coated Serrapeptase - Total Body Support - 90 Vegetarian Capsules - AST Enzymes

    Features:

  • ✔ ADVANCED SYSTEMIC ENZYME FORMULA: Exclzyme is a potent blend of serrapeptase, proteases and herbs that support the body’s natural response to inflammation and healthy joint function. The Exclzyme formula has been used for more than a decade by thousands of people as a daily dietary supplement.*
  • ✔ RANGE OF USE: Supports the body’s natural response to inflammation including fatigued muscles and joint function, healthy blood circulation, and healthy fibrin metabolism.*
  • ✔ ACHIEVE OPTIMUM HEALTH: Elimination of potentially waste substances from the body is a crucial part in the metabolic processes for optimal health. A variety of health issues can develop if excess waste within the body impair enzyme function or without a proper store of enzymes. Exclzyme improves the body’s ability to rid of these wastes and brings it to a healthy normal balance.
  • ✔ QUALITY ASSURED: All products by AST Enzymes are manufactured in the USA. All products are made in a FDA registered facility that follows GMP guidelines. Free of pesticides, chemicals, preservatives, animal derivatives, dairy, yeast, fish or shellfish, peanuts, and tree nuts. All individual enzymes are kosher-certified ingredients, and suitable for vegetarians and vegans.

Vitälzym Original Proteolytic Systemic Digestive Enzyme Formula Serrapeptase Source | Anti-Inflammatory Immune and Joint Support Increase Blood Flow Cardio Function | Healthy Men Women (90 Capsules)

Vitälzym Original Proteolytic Systemic Digestive Enzyme Formula Serrapeptase Source | Anti-Inflammatory Immune and Joint Support Increase Blood Flow Cardio Function | Healthy Men Women (90 Capsules)

    Features:

  • American Made, Essential for Health, Plant Based: Not All Complete Digestive System Enzyme Products Are Made The Same – Pay For True Quality & You Will Not Be Disappointed. World Nutrition is a pioneer of complementary systemic enzymes. In 2001 we introduced the original Vitalzym pill as a hybrid formula that offers both systemic & digestive benefits to provide total body support. It quickly became the best-selling systemic enzyme in the world and sold over $10M in the first 3 years alone
  • The Best Vegetarian Digestion Supplement & Remedy: Our Premium Strength Super Gut Defense Formula contains everything you need for full-body support: Protease, Serrapeptase, Papain, Bromelain, Amylase, Lipase, Rutin, & Amla. Each powerful ingredient is derived from natural, vegetarian sources. Most competitors use enzymes harvested from pigs & cows after slaughter. These enzymes are low-quality & strength, requiring a much higher dose as they’re less effective against targeted mediators
  • Advanced, Broad Spectrum Caps Promote Wellness: Our complex extract provides the optimal potency level of proteolytic enzymes that may assist with IBS, gas, inflammation, regulating your immune system, removing excess plaque & fibrin (fibrous tissue), & support the return of blood volume & flow. Vitälzym capsules are formulated to support health in the following systems: cognitive/mental, upper respiratory, cardiovascular, gastrointestinal, reproductive, joints, connective tissue, & skin
  • Fast Response, Organic, Calms Indigestion & Assists With IBS, Gas, Bloating: Regain bowel comfort with our perfect synergistic blend of systemic and digestive enzymes. It starts in the stomach & helps the body to break down food and absorb nutrients. After helping increase digestive abilities, the systemic enzymes take action in the bloodstream, moving throughout your entire body. This unique combination can help to improve your bodily processes and regain your quality of life
  • Formulated for Active Vitality Enhancement Plus Recovery: High-quality pure powder filled capsules that break down in your stomach provide digestive support with every dose. Some serrapeptase survives the acidic environment of the stomach and a dosage is released in the small intestine, allowing it to be absorbed into your bloodstream and distributed throughout your whole body. Our customers have reported increased energy, stamina, and recovery from intense exercise

Fibrenza Systemic Enzyme 500mg 60 Capsules

Fibrenza Systemic Enzyme 500mg 60 Capsules

    Features:

  • Does NOT contain: phthalates, maltodextrin, dairy, wheat, yeast, gluten, fish, magnesium stearate, talc, artificial colors or flavors. Non-GMO

Medizym, Systemic Enzyme Formula, 200 Tablets

Medizym, Systemic Enzyme Formula, 200 Tablets

    Features:

  • Experimental and clinical studies show that the specific systemic enzymes such as those contained in Medizym work preventively to help the body maintain healthy immune system activity and low to normal inflammation levels, and that they support healthy aging.
  • Enzymes, like those in Medizym®, are involved in almost every metabolic process in the human body, including breathing, digestion, energy production, blood clotting, immune system function, and tissue and wound repair. However, as we age, the body’s enzyme levels become depleted, and most people’s diets, inundated with cooked and processed foods, no longer supply adequate enzymes.
  • With over 35 years of experience, Naturally Vitamins uses ingredients from the purest sources. Our state-of-the-art manufacturing facility meets and exceeds Good Manufacturing Practices (GMP) set for dietary supplements by the industry. At Naturally Vitamins, we believe that natural solutions are best for you—and the environment.
  • During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers’ recommendations, when provided.

Integrative Therapeutics – Bio-Zyme – Systemic Enzymes – Full-Strength Pancreatic Enzyme Complex to Support Digestive Health – 200 Tablets

Integrative Therapeutics - Bio-Zyme - Systemic Enzymes - Full-Strength Pancreatic Enzyme Complex to Support Digestive Health - 200 Tablets

    Features:

  • Supports digestion when taken with meals.
  • Promotes joint and immune health when taken between meals.
  • This product contains no salt, yeast, wheat, gluten, artificial coloring, artificial flavoring, preservatives.

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