Rank Product Name Score
1 Systane COMPLETE PF Multi-Dose Preservative Free Dry Eye Drops 20ml(Pack of 2 – 10mL bottles) Systane COMPLETE PF Multi-Dose Preservative Free Dry Eye Drops 20ml(Pack of 2 – 10mL bottles)
Alcon
9.8 GET ON AMAZON
2 Biotrue® Hydration Boost Eye Drops for Irritated and Dry Eyes from Bausch + Lomb, Preservative Free, Naturally Inspired, Soft Contact Lens Friendly, 0.33 FL OZ (10 mL), Pack of 2 Biotrue® Hydration Boost Eye Drops for Irritated and Dry Eyes from Bausch + Lomb, Preservative Free, Naturally Inspired, Soft Contact Lens Friendly, 0.33 FL OZ (10 mL), Pack of 2
Bausch & Lomb
9.4 GET ON AMAZON
3 TheraTears Dry Eye Therapy Lubricant Eye Drops for Dry Eyes, Preservative Free, 30 Vials TheraTears Dry Eye Therapy Lubricant Eye Drops for Dry Eyes, Preservative Free, 30 Vials
Prestige Consumer Healthcare
9.1 GET ON AMAZON
4 Bausch + Lomb Soothe Preservative-Free Lubricant Eye Drops, Box of 28 Single Use Dispensers Bausch + Lomb Soothe Preservative-Free Lubricant Eye Drops, Box of 28 Single Use Dispensers
Bausch & Lomb
9.0 GET ON AMAZON
5 TheraTears Nighttime Therapy Lubricant Eyedrops for Dry Eyes, Preservative Free, Single-Use Vials, Clear, 30 Count, 0.6 Fl Oz TheraTears Nighttime Therapy Lubricant Eyedrops for Dry Eyes, Preservative Free, Single-Use Vials, Clear, 30 Count, 0.6 Fl Oz
Prestige Consumer Healthcare
8.9 GET ON AMAZON
6 Refresh Relieva Preservative-Free Lubricant Eye Drops, 0.33 Fl Oz (Pack of 1) Refresh Relieva Preservative-Free Lubricant Eye Drops, 0.33 Fl Oz (Pack of 1)
Allergan, Inc. (Health and Personal Care)
8.7 GET ON AMAZON
7 Refresh Plus Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 50 Count, Packaging May Vary Refresh Plus Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 50 Count, Packaging May Vary
Allergan, Inc. (Health and Personal Care)
8.6 GET ON AMAZON
8 TheraTears Extra Dry Eye Therapy Lubricant Eye Drops for Dry Eyes, 0.5 fl oz, 2 Pack TheraTears Extra Dry Eye Therapy Lubricant Eye Drops for Dry Eyes, 0.5 fl oz, 2 Pack
Prestige Consumer Healthcare
8.4 GET ON AMAZON
9 ALCON Systane Hydration Preservative-Free Lubricant Eye Drops, Transparent, 0.6 Fl Oz, 30 Count ALCON Systane Hydration Preservative-Free Lubricant Eye Drops, Transparent, 0.6 Fl Oz, 30 Count
AmazonUs/ALFQ7
8.2 GET ON AMAZON
10 OPTASE Dry Eye Intense Drops - Preservative Free Eye Drops for Dry Eyes - Long Lasting Artificial Tears for Severe Dry Eye Relief - Convenient Multi-dose Bottle - Step 3 Hydrate - .33 fl oz, 300 Doses OPTASE Dry Eye Intense Drops – Preservative Free Eye Drops for Dry Eyes – Long Lasting Artificial Tears for Severe Dry Eye Relief – Convenient Multi-dose Bottle – Step 3 Hydrate – .33 fl oz, 300 Doses
Scope Health
8.2 GET ON AMAZON

Systane COMPLETE PF Multi-Dose Preservative Free Dry Eye Drops 20ml(Pack of 2 – 10mL bottles)

Systane COMPLETE PF Multi-Dose Preservative Free Dry Eye Drops 20ml(Pack of 2 – 10mL bottles)

    Features:

  • Fast acting hydration for sensitive eyes
  • Preservative free tear evaporation protection
  • Nano droplets for better coverage

Biotrue® Hydration Boost Eye Drops for Irritated and Dry Eyes from Bausch + Lomb, Preservative Free, Naturally Inspired, Soft Contact Lens Friendly, 0.33 FL OZ (10 mL), Pack of 2

Biotrue® Hydration Boost Eye Drops for Irritated and Dry Eyes from Bausch + Lomb, Preservative Free, Naturally Inspired, Soft Contact Lens Friendly, 0.33 FL OZ (10 mL), Pack of 2

    Features:

  • NATURALLY INSPIRED INGREDIENTS: Biotrue Hydration Boost Eye Drops are enhanced with HA (Hyaluronan), Antioxidant, and Electrolyte and provide instant moisture for dry eyes.
  • CONTACT LENS FRIENDLY: Biotrue Hydration Boost Eye Drops can be applied while wearing soft contact lenses.
  • INSTANT MOISTURE: For dry, irritated eyes due to screen and environmental stressors.
  • BIOTRUE EYE DROPS: Not only are the Hydration Boost Eye Drops free of preservatives but they are also pH balanced.
  • EYE DROPS & MORE: Bausch + Lomb makes eye care products you can trust, from contact lens solution to eye drops, vitamins, & ointments to help your eyes feel moisturized and protected.

TheraTears Dry Eye Therapy Lubricant Eye Drops for Dry Eyes, Preservative Free, 30 Vials

TheraTears Dry Eye Therapy Lubricant Eye Drops for Dry Eyes, Preservative Free, 30 Vials

    Features:

  • TheraTears Dry Eye Therapy Lubricant Eye Drops, Preservative Free, provide immediate, long-lasting relief of dry eye symptoms
  • TheraTears contains the 5 vital electrolytes found in natural tears
  • TheraTears corrects the salt imbalance that can cause dry eye symptoms
  • Preservative free for sensitive eyes; the single-use vials come in a foil pouch to ensure freshness
  • Doctor recommended and created; TheraTears was created by an ophthalmologist after 18 years of research

Bausch + Lomb Soothe Preservative-Free Lubricant Eye Drops, Box of 28 Single Use Dispensers

Bausch + Lomb Soothe Preservative-Free Lubricant Eye Drops, Box of 28 Single Use Dispensers

    Features:

  • LONG LASTING, FAST RELIEF DRY EYE THERAPY: Use Soothe Lubricant Eye Drops to help moisturize & refresh dry eyes for long-lasting relief & comfort Formulated to relieve dryness of the eye & help prevent irritation
  • DRY EYE DROPS: Tear replacement drops are important to help relieve dry eye symptoms
  • BAUSCH + LOMB EYE DROPS: Whether you have dry eyes, red eyes, itchy eyes, or all of the above, we offer a variety of options for your needs, including lubricating & preservative-free eye drops
  • EYE CARE EXPERTS: For over 150 years, Bausch + Lomb has focused on innovation & quality in our eye care products, from contact lenses & solutions to eye drops, ointments, eye vitamins & more
  • EYE DROPS & MORE: Bausch + Lomb makes eye care products you can trust, from contact lens solution to eye drops, vitamins, & ointments to make sure your eyes feel healthy, moisturized, & protected

TheraTears Nighttime Therapy Lubricant Eyedrops for Dry Eyes, Preservative Free, Single-Use Vials, Clear, 30 Count, 0.6 Fl Oz

TheraTears Nighttime Therapy Lubricant Eyedrops for Dry Eyes, Preservative Free, Single-Use Vials, Clear, 30 Count, 0.6 Fl Oz

    Features:

  • DRY EYE RELIEF: Use ThereTears Liquid Gel Nighttime Dry Eye Therapy Lubricant Eye Gel for soothing overnight relief of dry eye symptoms
  • RESTORE EYES NATURAL BALANCE: TheraTears electrolyte formula corrects the salt imbalance that can cause dry eye symptoms
  • UNIQUE SOLUTION: Utilizes a one of a kind hypotonic and electrolyte balanced formula that replicates healthy tears
  • PRESERVATIVE FREE: TheraTears is preservative free for sensitive eyes. The single-use vials come in a foil pouch to ensure they are as fresh as natural tears.
  • DOCTOR CREATED: TheraTears is not only recommmended by doctors, it was created by an Ophthalmologist after 18 years of research.

Refresh Relieva Preservative-Free Lubricant Eye Drops, 0.33 Fl Oz (Pack of 1)

Refresh Relieva Preservative-Free Lubricant Eye Drops, 0.33 Fl Oz (Pack of 1)

    Features:

  • Innovative, preservative-free formula in a multidose bottle
  • Relieves discomfort due to dry, irritated eyes
  • Prevents further irritation
  • Hydrocell technology enables hydration and maintains the volume of cells on the eye’s surface
  • Patented multidose bottle with a double locked system keeps drops sterile
  • Recommended for sensitive eyes
  • Can be used after LASIK or other eye surgeries. Follow your eye doctor’s instructions if you are using REFRESH RELIEVA PF after an eye surgery (e.g., LASIK) to relieve dryness and discomfort
  • On-the-go single use vials

Refresh Plus Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 50 Count, Packaging May Vary

Refresh Plus Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 50 Count, Packaging May Vary

    Features:

  • Original strength, preservative-free formula
  • Relieves mild symptoms of eye dryness
  • Instantly moisturizes and lubricates
  • Designed to act like your own natural tears
  • Great for sensitive eyes
  • Value size: 50 on-the go, single-use vials
  • Can be used after LASIK or other eye surgeries. Follow your eye doctor’s instructions if you are using REFRESH RELIEVA PF after an eye surgery (e.g., LASIK) to relieve dryness and discomfort.
  • The brand in preservative-free artificial tears; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

TheraTears Extra Dry Eye Therapy Lubricant Eye Drops for Dry Eyes, 0.5 fl oz, 2 Pack

TheraTears Extra Dry Eye Therapy Lubricant Eye Drops for Dry Eyes, 0.5 fl oz, 2 Pack

    Features:

  • TheraTears EXTRA Dry Eye Therapy Lubricant Eye Drops provide EXTRAordinary relief
  • Lubricant eye drops for extra dry eyes rehydrate, protect against further irritation and support a natural tear pH level
  • TheraTears contains the 5 vital electrolytes found in natural tears
  • TheraTears’ corrects the salt imbalance that can cause dry eye symptoms
  • Doctor recommended and created; TheraTears was created by an ophthalmologist after 18 years of research

ALCON Systane Hydration Preservative-Free Lubricant Eye Drops, Transparent, 0.6 Fl Oz, 30 Count

ALCON Systane Hydration Preservative-Free Lubricant Eye Drops, Transparent, 0.6 Fl Oz, 30 Count

    Features:

  • Hydrates fast and provides long-lasting relief.
  • #1 Doctor & pharmacist Recommended brand
  • Preservative free
  • Contains hyaluronate for advanced hydration
  • Safe for use with all contact lenses

OPTASE Dry Eye Intense Drops – Preservative Free Eye Drops for Dry Eyes – Long Lasting Artificial Tears for Severe Dry Eye Relief – Convenient Multi-dose Bottle – Step 3 Hydrate – .33 fl oz, 300 Doses

OPTASE Dry Eye Intense Drops - Preservative Free Eye Drops for Dry Eyes - Long Lasting Artificial Tears for Severe Dry Eye Relief - Convenient Multi-dose Bottle - Step 3 Hydrate - .33 fl oz, 300 Doses

    Features:

  • MOISTURIZE AND PROTECT: Made of glycerin and quality ingredients, OPTASE Dry Eye Intense Drops mix with the natural oils needed to protect your tears and hydrate your eyes to improve tear quality
  • PRESERVATIVE FREE: OPTASE Intense Eye Drops is the only product of its kind to provide a preservative free combination of ingredients designed to treat dry eye symptoms in a unique multi-dose bottle
  • MODERATE TO SEVERE DRY EYE RELIEF: The long lasting formulation of OPTASE Intense provides comfort for dry eye and post operative symptoms. And it is contact lens safe, providing relief when needed
  • ADVANCED BOTTLE TECHNOLOGY: A convenient multi-use drop bottle with advanced technology maintains sterility over 3 months without preservatives. Avoid the hassle of individual vials while on the go
  • COMPLETE DOCTOR RECOMMENDED EYE CARE RELIEF: OPTASE is the expert recommended 3-step regimen to help tackle the cause and symptoms of Dry Eyes, Blepharitis and Meibomian Gland Dysfunction (MGD)

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